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Mitochondrial localization of vitamin D receptor in human platelets and differentiated megakaryocytes.

PloS one | 2010

Like other steroid hormones, vitamin D elicits both transcriptional events and rapid non genomic effects. Vitamin D receptor (VDR) localization and mechanisms of VDR-triggered non genomic responses are still controversial. Although anticoagulant effects of vitamin D have been reported and VDR signalling has been characterized in monocytes and vascular cells, nothing is known about VDR expression and functions in human platelets, anucleated fragments of megakaryocytes which are known targets of other steroids.

Pubmed ID: 20107497 RIS Download

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MEG-01 (tool)

RRID:CVCL_0425

Cell line MEG-01 is a Cancer cell line with a species of origin Homo sapiens (Human)

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