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The Gene Ontology in 2010: extensions and refinements.

The Gene Ontology (GO) Consortium (http://www.geneontology.org) (GOC) continues to develop, maintain and use a set of structured, controlled vocabularies for the annotation of genes, gene products and sequences. The GO ontologies are expanding both in content and in structure. Several new relationship types have been introduced and used, along with existing relationships, to create links between and within the GO domains. These improve the representation of biology, facilitate querying, and allow GO developers to systematically check for and correct inconsistencies within the GO. Gene product annotation using GO continues to increase both in the number of total annotations and in species coverage. GO tools, such as OBO-Edit, an ontology-editing tool, and AmiGO, the GOC ontology browser, have seen major improvements in functionality, speed and ease of use.

Pubmed ID: 19920128


  • Gene Ontology Consortium


Nucleic acids research

Publication Data

January 22, 2010

Associated Grants

  • Agency: NHGRI NIH HHS, Id: #P41HG02273
  • Agency: Medical Research Council, Id: G0500293
  • Agency: NHGRI NIH HHS, Id: HG000330
  • Agency: NHGRI NIH HHS, Id: HG002659
  • Agency: NHGRI NIH HHS, Id: HG003751
  • Agency: NHGRI NIH HHS, Id: HG004341
  • Agency: NHGRI NIH HHS, Id: HG01315
  • Agency: NHGRI NIH HHS, Id: HG02223
  • Agency: NHLBI NIH HHS, Id: HL64541
  • Agency: NHGRI NIH HHS, Id: P41 HG003751
  • Agency: NHGRI NIH HHS, Id: P41 HG02273
  • Agency: British Heart Foundation, Id: SP/07/007/23671
  • Agency: NIGMS NIH HHS, Id: U24GM077905
  • Agency: NIGMS NIH HHS, Id: U24GM088849

Mesh Terms

  • Animals
  • Computational Biology
  • Databases, Genetic
  • Databases, Nucleic Acid
  • Databases, Protein
  • Genomics
  • Humans
  • Information Storage and Retrieval
  • Internet
  • Software
  • User-Computer Interface
  • Vocabulary, Controlled