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WormBase: a comprehensive resource for nematode research.

WormBase (http://www.wormbase.org) is a central data repository for nematode biology. Initially created as a service to the Caenorhabditis elegans research field, WormBase has evolved into a powerful research tool in its own right. In the past 2 years, we expanded WormBase to include the complete genomic sequence, gene predictions and orthology assignments from a range of related nematodes. This comparative data enrich the C. elegans data with improved gene predictions and a better understanding of gene function. In turn, they bring the wealth of experimental knowledge of C. elegans to other systems of medical and agricultural importance. Here, we describe new species and data types now available at WormBase. In addition, we detail enhancements to our curatorial pipeline and website infrastructure to accommodate new genomes and an extensive user base.

Pubmed ID: 19910365


  • Harris TW
  • Antoshechkin I
  • Bieri T
  • Blasiar D
  • Chan J
  • Chen WJ
  • De La Cruz N
  • Davis P
  • Duesbury M
  • Fang R
  • Fernandes J
  • Han M
  • Kishore R
  • Lee R
  • Müller HM
  • Nakamura C
  • Ozersky P
  • Petcherski A
  • Rangarajan A
  • Rogers A
  • Schindelman G
  • Schwarz EM
  • Tuli MA
  • Van Auken K
  • Wang D
  • Wang X
  • Williams G
  • Yook K
  • Durbin R
  • Stein LD
  • Spieth J
  • Sternberg PW


Nucleic acids research

Publication Data

January 22, 2010

Associated Grants

  • Agency: Medical Research Council, Id: G0701197
  • Agency: NHGRI NIH HHS, Id: P41-HG02223
  • Agency: NHGRI NIH HHS, Id: P41HG02223
  • Agency: Howard Hughes Medical Institute, Id:

Mesh Terms

  • Alleles
  • Animals
  • Caenorhabditis
  • Caenorhabditis elegans
  • Computational Biology
  • Databases, Genetic
  • Databases, Nucleic Acid
  • Databases, Protein
  • Information Storage and Retrieval
  • Internet
  • Phenotype
  • Protein Structure, Tertiary
  • Software
  • Transcription Factors