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WormBase: a comprehensive resource for nematode research.

Nucleic acids research | 2010

WormBase (http://www.wormbase.org) is a central data repository for nematode biology. Initially created as a service to the Caenorhabditis elegans research field, WormBase has evolved into a powerful research tool in its own right. In the past 2 years, we expanded WormBase to include the complete genomic sequence, gene predictions and orthology assignments from a range of related nematodes. This comparative data enrich the C. elegans data with improved gene predictions and a better understanding of gene function. In turn, they bring the wealth of experimental knowledge of C. elegans to other systems of medical and agricultural importance. Here, we describe new species and data types now available at WormBase. In addition, we detail enhancements to our curatorial pipeline and website infrastructure to accommodate new genomes and an extensive user base.

Pubmed ID: 19910365 RIS Download

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Associated grants

  • Agency: Medical Research Council, United Kingdom
    Id: G0701197
  • Agency: Howard Hughes Medical Institute, United States
  • Agency: NHGRI NIH HHS, United States
    Id: P41-HG02223
  • Agency: NHGRI NIH HHS, United States
    Id: P41HG02223

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This is a list of tools and resources that we have found mentioned in this publication.


Gene Ontology (tool)

RRID:SCR_002811

Computable knowledge regarding functions of genes and gene products. GO resources include biomedical ontologies that cover molecular domains of all life forms as well as extensive compilations of gene product annotations to these ontologies that provide largely species-neutral, comprehensive statements about what gene products do. Used to standardize representation of gene and gene product attributes across species and databases.

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GBrowse syn (tool)

RRID:SCR_012971

A GBrowse-based synteny browser designed to display multiple genomes, with a central reference species compared to two or more additional species.

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