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The UCSC Genome Browser database: update 2010.

The University of California, Santa Cruz (UCSC) Genome Browser website ( provides a large database of publicly available sequence and annotation data along with an integrated tool set for examining and comparing the genomes of organisms, aligning sequence to genomes, and displaying and sharing users' own annotation data. As of September 2009, genomic sequence and a basic set of annotation 'tracks' are provided for 47 organisms, including 14 mammals, 10 non-mammal vertebrates, 3 invertebrate deuterostomes, 13 insects, 6 worms and a yeast. New data highlights this year include an updated human genome browser, a 44-species multiple sequence alignment track, improved variation and phenotype tracks and 16 new genome-wide ENCODE tracks. New features include drag-and-zoom navigation, a Wiki track for user-added annotations, new custom track formats for large datasets (bigBed and bigWig), a new multiple alignment output tool, links to variation and protein structure tools, in silico PCR utility enhancements, and improved track configuration tools.

Pubmed ID: 19906737


  • Rhead B
  • Karolchik D
  • Kuhn RM
  • Hinrichs AS
  • Zweig AS
  • Fujita PA
  • Diekhans M
  • Smith KE
  • Rosenbloom KR
  • Raney BJ
  • Pohl A
  • Pheasant M
  • Meyer LR
  • Learned K
  • Hsu F
  • Hillman-Jackson J
  • Harte RA
  • Giardine B
  • Dreszer TR
  • Clawson H
  • Barber GP
  • Haussler D
  • Kent WJ


Nucleic acids research

Publication Data

January 22, 2010

Associated Grants

  • Agency: NHGRI NIH HHS, Id: 1U54HG004555-01
  • Agency: NIDDK NIH HHS, Id: 2 R01 DK065806-06
  • Agency: NHGRI NIH HHS, Id: 5P41HG002371-09
  • Agency: NHGRI NIH HHS, Id: 5U41HG004568-02
  • Agency: NHGRI NIH HHS, Id: U54 HG004555
  • Agency: Howard Hughes Medical Institute, Id:

Mesh Terms

  • Animals
  • Computational Biology
  • Databases, Genetic
  • Databases, Nucleic Acid
  • Genetic Variation
  • Genome
  • Genome, Fungal
  • Genomics
  • Humans
  • Information Storage and Retrieval
  • Internet
  • Invertebrates
  • Models, Molecular
  • Phenotype
  • Software