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The Universal Protein Resource (UniProt) in 2010.

The primary mission of UniProt is to support biological research by maintaining a stable, comprehensive, fully classified, richly and accurately annotated protein sequence knowledgebase, with extensive cross-references and querying interfaces freely accessible to the scientific community. UniProt is produced by the UniProt Consortium which consists of groups from the European Bioinformatics Institute (EBI), the Swiss Institute of Bioinformatics (SIB) and the Protein Information Resource (PIR). UniProt is comprised of four major components, each optimized for different uses: the UniProt Archive, the UniProt Knowledgebase, the UniProt Reference Clusters and the UniProt Metagenomic and Environmental Sequence Database. UniProt is updated and distributed every 3 weeks and can be accessed online for searches or download at

Pubmed ID: 19843607


  • UniProt Consortium


Nucleic acids research

Publication Data

January 22, 2010

Associated Grants

  • Agency: NHGRI NIH HHS, Id: 2P41HG02273-07
  • Agency: NIGMS NIH HHS, Id: 5R01GM080646-04
  • Agency: PHS HHS, Id: HHSN266200400061C
  • Agency: NHGRI NIH HHS, Id: U01HG02712

Mesh Terms

  • Algorithms
  • Animals
  • Computational Biology
  • Databases, Nucleic Acid
  • Databases, Protein
  • Europe
  • Genome, Fungal
  • Genome, Viral
  • Humans
  • Information Storage and Retrieval
  • Internet
  • Protein Isoforms
  • Proteome
  • Proteomics
  • Software