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Dissecting the phenotype in genome-wide association studies of psychiatric illness.

Over the past 2 years genome-wide association studies have made major contributions to understanding the genetic architecture of many common human diseases. This editorial outlines the development of such studies in psychiatry and highlights the opportunities for advancing understanding of the biological underpinnings and nosological structure of psychiatric disorders.

Pubmed ID: 19648536

Authors

  • Cross-Disorder Phenotype Group of the Psychiatric GWAS Consortium
  • Craddock N
  • Kendler K
  • Neale M
  • Nurnberger J
  • Purcell S
  • Rietschel M
  • Perlis R
  • Santangelo SL
  • Schulze TG
  • Schulze T
  • Smoller JW
  • Thapar A

Journal

The British journal of psychiatry : the journal of mental science

Publication Data

August 3, 2009

Associated Grants

  • Agency: NIMH NIH HHS, Id: U01 MH085520

Mesh Terms

  • Adult
  • Genome-Wide Association Study
  • Humans
  • Mental Disorders
  • Phenotype