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Topographical and temporal diversity of the human skin microbiome.

Science (New York, N.Y.) | May 29, 2009

Human skin is a large, heterogeneous organ that protects the body from pathogens while sustaining microorganisms that influence human health and disease. Our analysis of 16S ribosomal RNA gene sequences obtained from 20 distinct skin sites of healthy humans revealed that physiologically comparable sites harbor similar bacterial communities. The complexity and stability of the microbial community are dependent on the specific characteristics of the skin site. This topographical and temporal survey provides a baseline for studies that examine the role of bacterial communities in disease states and the microbial interdependencies required to maintain healthy skin.

Pubmed ID: 19478181 RIS Download

Mesh terms: Actinobacteria | Adult | Bacteria | Bacteroidetes | Biodiversity | Female | Genes, rRNA | Humans | Male | Metagenome | Molecular Sequence Data | Phylogeny | Proteobacteria | RNA, Ribosomal, 16S | Skin | Time Factors | Young Adult

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Associated grants

  • Agency: Intramural NIH HHS, Id: Z01 HG000180-08
  • Agency: Intramural NIH HHS, Id: ZIA BC010938-02
  • Agency: Intramural NIH HHS, Id: ZIA HG000180-09

Mouse Genome Informatics (Data, Gene Annotation)

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