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Approximately 10% of Caenorhabditis elegans nervous system synapses are electrical, that is, gap junctions composed of innexins. The locomotory nervous system consists of several pairs of interneurons and three major classes of motor neurons, all with stereotypical patterns of connectivity that include gap junctions. Mutations in the two innexin genes unc-7 and unc-9 result in identical uncoordinated movement phenotypes, and their respective gene products were investigated for their contribution to electrical synapse connectivity.
Pubmed ID: 19432959 RIS Download
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Mus musculus with name CC007/Unc from IMSR.
View all literature mentionsMus musculus with name CC007/Unc from IMSR.
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