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CellML metadata standards, associated tools and repositories.

The development of standards for encoding mathematical models is an important component of model building and model sharing among scientists interested in understanding multi-scale physiological processes. CellML provides such a standard, particularly for models based on biophysical mechanisms, and a substantial number of models are now available in the CellML Model Repository. However, there is an urgent need to extend the current CellML metadata standard to provide biological and biophysical annotation of the models in order to facilitate model sharing, automated model reduction and connection to biological databases. This paper gives a broad overview of a number of new developments on CellML metadata and provides links to further methodological details available from the CellML website.

Pubmed ID: 19380315


  • Beard DA
  • Britten R
  • Cooling MT
  • Garny A
  • Halstead MD
  • Hunter PJ
  • Lawson J
  • Lloyd CM
  • Marsh J
  • Miller A
  • Nickerson DP
  • Nielsen PM
  • Nomura T
  • Subramanium S
  • Wimalaratne SM
  • Yu T


Philosophical transactions. Series A, Mathematical, physical, and engineering sciences

Publication Data

May 28, 2009

Associated Grants

  • Agency: Wellcome Trust, Id:

Mesh Terms

  • Biophysics
  • Computer Simulation
  • Database Management Systems
  • Programming Languages