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Ascl1 is a required downstream effector of Gsx gene function in the embryonic mouse telencephalon.

Neural development | 2009

The homeobox gene Gsx2 (formerly Gsh2) is known to regulate patterning in the lateral ganglionic eminence (LGE) of the embryonic telencephalon. In its absence, the closely related gene Gsx1 (previously known as Gsh1) can partially compensate in the patterning and differentiation of ventral telencephalic structures, such as the striatum. However, the cellular and molecular mechanisms underlying this compensation remain unclear.

Pubmed ID: 19208224 RIS Download

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Associated grants

  • Agency: Medical Research Council, United Kingdom
    Id: MC_U117570528
  • Agency: NICHD NIH HHS, United States
    Id: HD046387
  • Agency: NIMH NIH HHS, United States
    Id: MH069643
  • Agency: NINDS NIH HHS, United States
    Id: R01 NS044080
  • Agency: NIDCD NIH HHS, United States
    Id: F30 DC008928
  • Agency: NICHD NIH HHS, United States
    Id: T32 HD046387
  • Agency: NIMH NIH HHS, United States
    Id: R01 MH069643
  • Agency: NINDS NIH HHS, United States
    Id: R56 NS044080
  • Agency: NINDS NIH HHS, United States
    Id: NS044080
  • Agency: NINDS NIH HHS, United States
    Id: R01 NS044080-07A1
  • Agency: NIDCD NIH HHS, United States
    Id: DC008928

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C57BL/6J (tool)

RRID:IMSR_JAX:000664

Mus musculus with name C57BL/6J from IMSR.

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