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The 2008 update of the Aspergillus nidulans genome annotation: a community effort.

The identification and annotation of protein-coding genes is one of the primary goals of whole-genome sequencing projects, and the accuracy of predicting the primary protein products of gene expression is vital to the interpretation of the available data and the design of downstream functional applications. Nevertheless, the comprehensive annotation of eukaryotic genomes remains a considerable challenge. Many genomes submitted to public databases, including those of major model organisms, contain significant numbers of wrong and incomplete gene predictions. We present a community-based reannotation of the Aspergillus nidulans genome with the primary goal of increasing the number and quality of protein functional assignments through the careful review of experts in the field of fungal biology.

Pubmed ID: 19146970

Authors

  • Wortman JR
  • Gilsenan JM
  • Joardar V
  • Deegan J
  • Clutterbuck J
  • Andersen MR
  • Archer D
  • Bencina M
  • Braus G
  • Coutinho P
  • von Döhren H
  • Doonan J
  • Driessen AJ
  • Durek P
  • Espeso E
  • Fekete E
  • Flipphi M
  • Estrada CG
  • Geysens S
  • Goldman G
  • de Groot PW
  • Hansen K
  • Harris SD
  • Heinekamp T
  • Helmstaedt K
  • Henrissat B
  • Hofmann G
  • Homan T
  • Horio T
  • Horiuchi H
  • James S
  • Jones M
  • Karaffa L
  • Karányi Z
  • Kato M
  • Keller N
  • Kelly DE
  • Kiel JA
  • Kim JM
  • van der Klei IJ
  • Klis FM
  • Kovalchuk A
  • Krasevec N
  • Kubicek CP
  • Liu B
  • Maccabe A
  • Meyer V
  • Mirabito P
  • Miskei M
  • Mos M
  • Mullins J
  • Nelson DR
  • Nielsen J
  • Oakley BR
  • Osmani SA
  • Pakula T
  • Paszewski A
  • Paulsen I
  • Pilsyk S
  • Pócsi I
  • Punt PJ
  • Ram AF
  • Ren Q
  • Robellet X
  • Robson G
  • Seiboth B
  • van Solingen P
  • Specht T
  • Sun J
  • Taheri-Talesh N
  • Takeshita N
  • Ussery D
  • vanKuyk PA
  • Visser H
  • van de Vondervoort PJ
  • de Vries RP
  • Walton J
  • Xiang X
  • Xiong Y
  • Zeng AP
  • Brandt BW
  • Cornell MJ
  • van den Hondel CA
  • Visser J
  • Oliver SG
  • Turner G

Journal

Fungal genetics and biology : FG & B

Publication Data

March 2, 2009

Associated Grants

  • Agency: Biotechnology and Biological Sciences Research Council, Id: BB/F004389/1
  • Agency: NIAID NIH HHS, Id: N01 AI030071
  • Agency: NIGMS NIH HHS, Id: R01 GM031837
  • Agency: Biotechnology and Biological Sciences Research Council, Id:

Mesh Terms

  • Aspergillus nidulans
  • Fungal Proteins
  • Genes, Fungal
  • Genome, Fungal
  • Genomics