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Skeletal muscle-specific deletion of lipoprotein lipase enhances insulin signaling in skeletal muscle but causes insulin resistance in liver and other tissues.

Diabetes | 2009

Skeletal muscle-specific LPL knockout mouse (SMLPL(-/-)) were created to study the systemic impact of reduced lipoprotein lipid delivery in skeletal muscle on insulin sensitivity, body weight, and composition.

Pubmed ID: 18952837 RIS Download

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Associated grants

  • Agency: NIDDK NIH HHS, United States
    Id: U24: DK-76169
  • Agency: NIDDK NIH HHS, United States
    Id: U24 DK076169
  • Agency: NIDDK NIH HHS, United States
    Id: P30 DK048520
  • Agency: NIDDK NIH HHS, United States
    Id: P30DK048520
  • Agency: NIDDK NIH HHS, United States
    Id: P30: DK-45735
  • Agency: NIDDK NIH HHS, United States
    Id: U24 DK059635
  • Agency: NIDDK NIH HHS, United States
    Id: R01 DK040936
  • Agency: NIDDK NIH HHS, United States
    Id: P30 DK045735
  • Agency: NIDDK NIH HHS, United States
    Id: DK-26356
  • Agency: NIDDK NIH HHS, United States
    Id: R01:DK-40936
  • Agency: NIDDK NIH HHS, United States
    Id: DK-059767
  • Agency: NIDDK NIH HHS, United States
    Id: R01 DK080756

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