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FlyBase: enhancing Drosophila Gene Ontology annotations.

FlyBase (http://flybase.org) is a database of Drosophila genetic and genomic information. Gene Ontology (GO) terms are used to describe three attributes of wild-type gene products: their molecular function, the biological processes in which they play a role, and their subcellular location. This article describes recent changes to the FlyBase GO annotation strategy that are improving the quality of the GO annotation data. Many of these changes stem from our participation in the GO Reference Genome Annotation Project--a multi-database collaboration producing comprehensive GO annotation sets for 12 diverse species.

Pubmed ID: 18948289


  • Tweedie S
  • Ashburner M
  • Falls K
  • Leyland P
  • McQuilton P
  • Marygold S
  • Millburn G
  • Osumi-Sutherland D
  • Schroeder A
  • Seal R
  • Zhang H
  • FlyBase Consortium


Nucleic acids research

Publication Data

January 16, 2009

Associated Grants

  • Agency: Medical Research Council, Id: G0500293
  • Agency: Medical Research Council, Id: G8225539
  • Agency: NHGRI NIH HHS, Id: P41 HG00739
  • Agency: NIGMS NIH HHS, Id: R25 GM060201

Mesh Terms

  • Animals
  • Databases, Genetic
  • Drosophila
  • Drosophila Proteins
  • Genes, Insect
  • Genome, Insect
  • Genomics
  • Vocabulary, Controlled