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NVP-AUY922: a small molecule HSP90 inhibitor with potent antitumor activity in preclinical breast cancer models.

Breast cancer research : BCR | 2008

Heat shock protein 90 (HSP90) is a key component of a multichaperone complex involved in the post-translational folding of a large number of client proteins, many of which play essential roles in tumorigenesis. HSP90 has emerged in recent years as a promising new target for anticancer therapies.

Pubmed ID: 18430202 RIS Download

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BT-474 (tool)

RRID:CVCL_0179

Cell line BT-474 is a Cancer cell line with a species of origin Homo sapiens (Human)

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