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Nogo-66 receptor antagonist peptide (NEP1-40) administration promotes functional recovery and axonal growth after lateral funiculus injury in the adult rat.

Neurorehabilitation and neural repair | 2008

The myelin protein Nogo inhibits axon regeneration by binding to its receptor (NgR) on axons. Intrathecal delivery of an NgR antagonist (NEP1-40) promotes growth of injured corticospinal axons and recovery of motor function following a dorsal hemisection. The authors used a similar design to examine recovery and repair after a lesion that interrupts the rubrospinal tract (RST).

Pubmed ID: 18056009 RIS Download

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Associated grants

  • Agency: NINDS NIH HHS, United States
    Id: NS24707
  • Agency: NINDS NIH HHS, United States
    Id: R37 NS033020
  • Agency: NINDS NIH HHS, United States
    Id: R01 NS039962-10
  • Agency: NINDS NIH HHS, United States
    Id: R01 NS039962
  • Agency: NINDS NIH HHS, United States
    Id: P50 NS024707
  • Agency: NINDS NIH HHS, United States
    Id: R01 NS042304-08
  • Agency: NICHD NIH HHS, United States
    Id: T32HD07467
  • Agency: NINDS NIH HHS, United States
    Id: R01 NS056485
  • Agency: NICHD NIH HHS, United States
    Id: T32 HD007467
  • Agency: NINDS NIH HHS, United States
    Id: R01 NS042304
  • Agency: NINDS NIH HHS, United States
    Id: R37 NS033020-17
  • Agency: NINDS NIH HHS, United States
    Id: R01 NS056485-04

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5-HT (Serotonin) Rabbit Antibody (antibody)

RRID:AB_572263

This polyclonal targets Serotonin

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