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JASPAR, the open access database of transcription factor-binding profiles: new content and tools in the 2008 update.

JASPAR is a popular open-access database for matrix models describing DNA-binding preferences for transcription factors and other DNA patterns. With its third major release, JASPAR has been expanded and equipped with additional functions aimed at both casual and power users. The heart of the JASPAR database-the JASPAR CORE sub-database-has increased by 12% in size, and three new specialized sub-databases have been added. New functions include clustering of matrix models by similarity, generation of random matrices by sampling from selected sets of existing models and a language-independent Web Service applications programming interface for matrix retrieval. JASPAR is available at http://jaspar.genereg.net.

Pubmed ID: 18006571

Authors

  • Bryne JC
  • Valen E
  • Tang MH
  • Marstrand T
  • Winther O
  • da Piedade I
  • Krogh A
  • Lenhard B
  • Sandelin A

Journal

Nucleic acids research

Publication Data

January 15, 2008

Associated Grants

None

Mesh Terms

  • Access to Information
  • Animals
  • Binding Sites
  • Computational Biology
  • Data Interpretation, Statistical
  • Databases, Nucleic Acid
  • Humans
  • Internet
  • Models, Genetic
  • Promoter Regions, Genetic
  • RNA Splice Sites
  • Regulatory Elements, Transcriptional
  • Software
  • Transcription Factors
  • User-Computer Interface