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Arabidopsis TANGLED identifies the division plane throughout mitosis and cytokinesis.

Current biology : CB | 2007

In premitotic plant cells, the future division plane is predicted by a cortical ring of microtubules and F-actin called the preprophase band (PPB). The PPB persists throughout prophase, but is disassembled upon nuclear-envelope breakdown as the mitotic spindle forms. Following nuclear division, a cytokinetic phragmoplast forms between the daughter nuclei and expands laterally to attach the new cell wall at the former PPB site. A variety of observations suggest that expanding phragmoplasts are actively guided to the former PPB site, but little is known about how plant cells "remember" this site after PPB disassembly.

Pubmed ID: 17964159 RIS Download

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Associated grants

  • Agency: NIGMS NIH HHS, United States
    Id: R01 GM053137
  • Agency: NIGMS NIH HHS, United States
    Id: R01 GM053137-10
  • Agency: NIGMS NIH HHS, United States
    Id: GM53137

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MetaMorph Microscopy Automation and Image Analysis Software (tool)

RRID:SCR_002368

Software tool for automated microscope acquisition, device control, and image analysis. Used for integrating dissimilar fluorescent microscope hardware and peripherals into a single custom workstation, while providing all the tools needed to perform analysis of acquired images. Offers user friendly application modules for analysis such as cell signaling, cell counting, and protein expression.

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