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Chemical Entities of Biological Interest (ChEBI) is a freely available dictionary of molecular entities focused on 'small' chemical compounds. The molecular entities in question are either natural products or synthetic products used to intervene in the processes of living organisms. Genome-encoded macromolecules (nucleic acids, proteins and peptides derived from proteins by cleavage) are not as a rule included in ChEBI. In addition to molecular entities, ChEBI contains groups (parts of molecular entities) and classes of entities. ChEBI includes an ontological classification, whereby the relationships between molecular entities or classes of entities and their parents and/or children are specified. ChEBI is available online at http://www.ebi.ac.uk/chebi/
Pubmed ID: 17932057 RIS Download
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Collection of data of protein sequence and functional information. Resource for protein sequence and annotation data. Consortium for preservation of the UniProt databases: UniProt Knowledgebase (UniProtKB), UniProt Reference Clusters (UniRef), and UniProt Archive (UniParc), UniProt Proteomes. Collaboration between European Bioinformatics Institute (EMBL-EBI), SIB Swiss Institute of Bioinformatics and Protein Information Resource. Swiss-Prot is a curated subset of UniProtKB.
View all literature mentionsRecognized as the world authority on chemical nomenclature, terminology, standardized methods for measurement, atomic weights and many other critically evaluated data, this scientific, international, non-governmental and objective body addresses many global issues involving the chemical sciences. It serves to advance the worldwide aspects of the chemical sciences and to contribute to the application of chemistry in the service of Humankind. The Union sponsors major international meetings that range from specialized scientific symposia to CHEMRAWN meetings with societal impact. * Projects: IUPAC encourages the submission of projects in all areas of chemistry relevant to its work. * Publications: IUPAC publishes books, journals, electronic resources, and issues many reports in all areas of chemistry * Conferences: Each year IUPAC sponsors a large number of symposia that cover a wide range of specialized topics in chemistry. * Members and bodies: Chemists throughout the world are engaged on a voluntary basis in the scientific work of IUPAC.
View all literature mentionsA multi-institutional effort to identify and quantitate, using a systems biology approach and sophisticated mass spectrometers, all of the major - and many minor - lipid species in mammalian cells, as well as to quantitate the changes in these species in response to perturbation. The goal of their research is to better understand lipid metabolism and the active role lipids play in diabetes, stroke, cancer, arthritis, Alzheimer's and other lipid-based diseases in order to facilitate development of more effective treatments. Resources available include: LIPID MAPS publications, detailed biochemical pathways, improved protocols for lipid separation and quantification, analytical tools for determining lipid quantitation, structure drawing tools for automatically drawing lipid molecular structures in stereochemical detail, and experimental data. The LIPID MAPS organization includes six lipidomics core laboratories, each specialized in extracting, identifying, and quantifying one of the major categories of mammalian lipids: fatty acyls, glycerolipids, glycerophospholipids, sphingolipids, sterol lipids, and prenol lipids. Other core laboratories and bridge projects include bioinformatics, mass spectrometric imaging, lipid synthesis, oxidized lipids, and macrophage biology and genomics.
View all literature mentionsInteractive and programmatic interfaces to query, browse and navigate an increasing number of biomedical ontologies and controlled vocabularies. It provides a web service interface to query multiple ontologies from a single location with a unified output format. It can integrate any ontology available in the Open Biomedical Ontology (OBO) format. The database can be queried to obtain information on a single term or to browse a complete ontology using AJAX. Auto-completion provides a user-friendly search mechanism. An AJAX-based ontology viewer is available to browse a complete ontology or subsets of it. A weekly MySQL database export file can be downloaded from the EBI public FTP directory.
View all literature mentionsCOMe is an attempt to classify metalloproteins and some other complex proteins using the concept of bioinorganic motif. COMe consists of three types of entities: Molecule (MOL), Bioinorganic Motif (BIM), and Bioinorganic Proteins (PRX). Both Molecule (MOL) and Bioinorganic Motif (BIM) entities consist of substructure elements. Substructure literally means that these elements can form parts of a bigger structure, i.e. complete protein. MOL is an entity representing small molecule (as opposed to macromolecule) which, in complex with polypeptide, forms a functional protein. Users can query by COMe ID or using a case sensitive or insensitive text search, use predefined queries, or look at the paths via the online ontology provided by COMe.
View all literature mentionsThe SciCrunch Infrastructure was developed as a cooperative data platform to be used by diverse communities in making data more FAIR.
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