Spinal muscular atrophy is caused by reduced levels of the survival of motor neurons (SMN) protein. SMN is found in large complexes with Sm proteins and at least eight other proteins, including seven "gemins". These complexes are involved in the assembly of snRNPs in the cytoplasm and their transport into the nucleus, but the precise roles of the individual protein components are largely unknown.
Pubmed ID: 17640370 RIS Download
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Cell line HeLa is a Cancer cell line with a species of origin Homo sapiens
View all literature mentionslaboratory mouse with name BALB/cAnNCrl from MGI.
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