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In Drosophila melanogaster dosage compensation of most X-linked genes is mediated by the male-specific lethal (MSL) complex, which includes MOF. MOF acetylates histone H4 at lysine 16 (H4K16ac). The X-linked Larval serum protein one alpha (Lsp1alpha) gene has long been known to be not dosage compensated. Here we have examined possible explanations for why the Lsp1alpha gene is not dosage compensated.
Pubmed ID: 17511883 RIS Download
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Tool to search translated nucleotide databases using a protein query.
View all literature mentionsWeb-based software used for the selection of best-fit models of protein evolution.
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