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Innovation adoption in substance abuse treatment: exposure, trialability, and the Clinical Trials Network.

Researchers and policymakers are increasingly focusing on factors that facilitate or impede the diffusion of evidence-based treatment techniques into routine clinical practice. One potentially fruitful avenue of research is the influence of involvement in research networks as a predictor of organizational innovation. The Clinical Trials Network (CTN) is examining a number of behavioral and pharmacological treatment techniques in controlled multisite studies. Using data from participating CTN treatment programs and large samples of programs outside the CTN, these analyses examine the influence of exposure to clinical trials on the subsequent adoption of buprenorphine and voucher-based motivational incentives. The analyses show that, controlling for a variety of organizational characteristics, direct exposure to buprenorphine clinical trials in the CTN significantly increased the odds of subsequent adoption. By contrast, the adoption of motivational incentives was entirely explained by organizational characteristics. The findings suggest that adoption of treatment innovations is a function of exposure, organizational resources, nature of innovations, and stage of the diffusion process.

Pubmed ID: 17481455


  • Ducharme LJ
  • Knudsen HK
  • Roman PM
  • Johnson JA


Journal of substance abuse treatment

Publication Data

June 7, 2007

Associated Grants

  • Agency: NIDA NIH HHS, Id: R01 DA013110
  • Agency: NIDA NIH HHS, Id: R01 DA013110-05
  • Agency: NIDA NIH HHS, Id: R01 DA014482
  • Agency: NIDA NIH HHS, Id: R01 DA014482-05
  • Agency: NIDA NIH HHS, Id: R01 DA13110
  • Agency: NIDA NIH HHS, Id: R01 DA14482

Mesh Terms

  • Analgesics, Opioid
  • Buprenorphine
  • Clinical Trials as Topic
  • Diffusion of Innovation
  • Evidence-Based Medicine
  • Health Services Research
  • Humans
  • Logistic Models
  • Multivariate Analysis
  • Substance-Related Disorders
  • Token Economy