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Pygo1 and Pygo2 roles in Wnt signaling in mammalian kidney development.

BMC biology | 2007

The pygopus gene of Drosophila encodes an essential component of the Armadillo (beta-catenin) transcription factor complex of canonical Wnt signaling. To better understand the functions of Pygopus-mediated canonical Wnt signaling in kidney development, targeted mutations were made in the two mammalian orthologs, Pygo1 and Pygo2.

Pubmed ID: 17425782 RIS Download

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Associated grants

  • Agency: NIDDK NIH HHS, United States
    Id: R01 DK061916
  • Agency: NIDDK NIH HHS, United States
    Id: DK61916

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Genovo (tool)

RRID:SCR_011911

Software for a novel de novo sequence assembler that discovers likely sequence reconstructions under the model.

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B6.C-Tg(CMV-cre)1Cgn/J (tool)

RRID:IMSR_JAX:006054

Mus musculus with name B6.C-Tg(CMV-cre)1Cgn/J from IMSR.

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