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Differentiation of Parkinson's disease and progressive supranuclear palsy with magnetic resonance imaging: the first Brazilian experience.

BACKGROUND: The objective of this study is to differentiate PSP from Parkinson's disease through magnetic resonance imaging. METHODS: We included 14 consecutive patients with PD (9) or PSP (5). These measures included the third ventricle, midbrain diameter, quadrigeminal plate, brainstem volumetry, and interpeduncular angle. RESULTS: Patients with PSP presented enlargement of third ventricle (100% vs. 33%), lower midbrain diameter (mean 13.2 +/- 1.7 mm vs. 16.5 +/- 1.7 mm) and thinning of the quadrigeminal plate (mean 2.7 +/- 0.3 mm vs. 3.6 +/- 0.3 mm) in comparison with PD. CONCLUSIONS: Characteristic findings on MRI may help to differentiate PD from PSP.

Pubmed ID: 17275393 RIS Download

Mesh terms: Aged | Brain | Brazil | Female | Humans | Magnetic Resonance Imaging | Male | Middle Aged | Parkinson Disease | Supranuclear Palsy, Progressive