• Register
X
Forgot Password

If you have forgotten your password you can enter your email here and get a temporary password sent to your email.

X

Leaving Community

Are you sure you want to leave this community? Leaving the community will revoke any permissions you have been granted in this community.

No
Yes

The genome of the sea urchin Strongylocentrotus purpuratus.

We report the sequence and analysis of the 814-megabase genome of the sea urchin Strongylocentrotus purpuratus, a model for developmental and systems biology. The sequencing strategy combined whole-genome shotgun and bacterial artificial chromosome (BAC) sequences. This use of BAC clones, aided by a pooling strategy, overcame difficulties associated with high heterozygosity of the genome. The genome encodes about 23,300 genes, including many previously thought to be vertebrate innovations or known only outside the deuterostomes. This echinoderm genome provides an evolutionary outgroup for the chordates and yields insights into the evolution of deuterostomes.

Pubmed ID: 17095691

Authors

  • Sea Urchin Genome Sequencing Consortium
  • Sodergren E
  • Weinstock GM
  • Davidson EH
  • Cameron RA
  • Gibbs RA
  • Angerer RC
  • Angerer LM
  • Arnone MI
  • Burgess DR
  • Burke RD
  • Coffman JA
  • Dean M
  • Elphick MR
  • Ettensohn CA
  • Foltz KR
  • Hamdoun A
  • Hynes RO
  • Klein WH
  • Marzluff W
  • McClay DR
  • Morris RL
  • Mushegian A
  • Rast JP
  • Smith LC
  • Thorndyke MC
  • Vacquier VD
  • Wessel GM
  • Wray G
  • Zhang L
  • Elsik CG
  • Ermolaeva O
  • Hlavina W
  • Hofmann G
  • Kitts P
  • Landrum MJ
  • Mackey AJ
  • Maglott D
  • Panopoulou G
  • Poustka AJ
  • Pruitt K
  • Sapojnikov V
  • Song X
  • Souvorov A
  • Solovyev V
  • Wei Z
  • Whittaker CA
  • Worley K
  • Durbin KJ
  • Shen Y
  • Fedrigo O
  • Garfield D
  • Haygood R
  • Primus A
  • Satija R
  • Severson T
  • Gonzalez-Garay ML
  • Jackson AR
  • Milosavljevic A
  • Tong M
  • Killian CE
  • Livingston BT
  • Wilt FH
  • Adams N
  • Bellé R
  • Carbonneau S
  • Cheung R
  • Cormier P
  • Cosson B
  • Croce J
  • Fernandez-Guerra A
  • Genevière AM
  • Goel M
  • Kelkar H
  • Morales J
  • Mulner-Lorillon O
  • Robertson AJ
  • Goldstone JV
  • Cole B
  • Epel D
  • Gold B
  • Hahn ME
  • Howard-Ashby M
  • Scally M
  • Stegeman JJ
  • Allgood EL
  • Cool J
  • Judkins KM
  • McCafferty SS
  • Musante AM
  • Obar RA
  • Rawson AP
  • Rossetti BJ
  • Gibbons IR
  • Hoffman MP
  • Leone A
  • Istrail S
  • Materna SC
  • Samanta MP
  • Stolc V
  • Tongprasit W
  • Tu Q
  • Bergeron KF
  • Brandhorst BP
  • Whittle J
  • Berney K
  • Bottjer DJ
  • Calestani C
  • Peterson K
  • Chow E
  • Yuan QA
  • Elhaik E
  • Graur D
  • Reese JT
  • Bosdet I
  • Heesun S
  • Marra MA
  • Schein J
  • Anderson MK
  • Brockton V
  • Buckley KM
  • Cohen AH
  • Fugmann SD
  • Hibino T
  • Loza-Coll M
  • Majeske AJ
  • Messier C
  • Nair SV
  • Pancer Z
  • Terwilliger DP
  • Agca C
  • Arboleda E
  • Chen N
  • Churcher AM
  • Hallböök F
  • Humphrey GW
  • Idris MM
  • Kiyama T
  • Liang S
  • Mellott D
  • Mu X
  • Murray G
  • Olinski RP
  • Raible F
  • Rowe M
  • Taylor JS
  • Tessmar-Raible K
  • Wang D
  • Wilson KH
  • Yaguchi S
  • Gaasterland T
  • Galindo BE
  • Gunaratne HJ
  • Juliano C
  • Kinukawa M
  • Moy GW
  • Neill AT
  • Nomura M
  • Raisch M
  • Reade A
  • Roux MM
  • Song JL
  • Su YH
  • Townley IK
  • Voronina E
  • Wong JL
  • Amore G
  • Branno M
  • Brown ER
  • Cavalieri V
  • Duboc V
  • Duloquin L
  • Flytzanis C
  • Gache C
  • Lapraz F
  • Lepage T
  • Locascio A
  • Martinez P
  • Matassi G
  • Matranga V
  • Range R
  • Rizzo F
  • Röttinger E
  • Beane W
  • Bradham C
  • Byrum C
  • Glenn T
  • Hussain S
  • Manning G
  • Miranda E
  • Thomason R
  • Walton K
  • Wikramanayke A
  • Wu SY
  • Xu R
  • Brown CT
  • Chen L
  • Gray RF
  • Lee PY
  • Nam J
  • Oliveri P
  • Smith J
  • Muzny D
  • Bell S
  • Chacko J
  • Cree A
  • Curry S
  • Davis C
  • Dinh H
  • Dugan-Rocha S
  • Fowler J
  • Gill R
  • Hamilton C
  • Hernandez J
  • Hines S
  • Hume J
  • Jackson L
  • Jolivet A
  • Kovar C
  • Lee S
  • Lewis L
  • Miner G
  • Morgan M
  • Nazareth LV
  • Okwuonu G
  • Parker D
  • Pu LL
  • Thorn R
  • Wright R

Journal

Science (New York, N.Y.)

Publication Data

November 10, 2006

Associated Grants

  • Agency: PHS HHS, Id: 2P42 ESO7381
  • Agency: NHGRI NIH HHS, Id: 5 U54 HG003273
  • Agency: NEI NIH HHS, Id: EY11930
  • Agency: PHS HHS, Id: F32 ESO12794
  • Agency: NICHD NIH HHS, Id: F32 HD047136
  • Agency: NICHD NIH HHS, Id: F32 HD047136-02
  • Agency: NICHD NIH HHS, Id: F32 HD047136-03
  • Agency: NICHD NIH HHS, Id: F32-HD47136
  • Agency: NIGMS NIH HHS, Id: GM058231
  • Agency: NIGMS NIH HHS, Id: GM070840
  • Agency: NIGMS NIH HHS, Id: GM61005
  • Agency: NIGMS NIH HHS, Id: GM61464
  • Agency: NICHD NIH HHS, Id: HD-37105
  • Agency: NICHD NIH HHS, Id: HD039948
  • Agency: NICHD NIH HHS, Id: HD14483
  • Agency: NICHD NIH HHS, Id: HD66219
  • Agency: NCI NIH HHS, Id: P30-CA14051
  • Agency: NIEHS NIH HHS, Id: R01 ES006272
  • Agency: NIEHS NIH HHS, Id: R01 ES006272-13
  • Agency: NIGMS NIH HHS, Id: R01 GM070840
  • Agency: NICHD NIH HHS, Id: R01 HD028152
  • Agency: NIEHS NIH HHS, Id: R01ES006272
  • Agency: NICHD NIH HHS, Id: R37-HD12896
  • Agency: NCRR NIH HHS, Id: RR-15044
  • Agency: Biotechnology and Biological Sciences Research Council, Id: S19916
  • Agency: NIGMS NIH HHS, Id: T32 GM007601
  • Agency: NHGRI NIH HHS, Id: U54 HG003273

Mesh Terms

  • Animals
  • Calcification, Physiologic
  • Cell Adhesion Molecules
  • Complement Activation
  • Computational Biology
  • Embryonic Development
  • Evolution, Molecular
  • Gene Expression Regulation, Developmental
  • Genes
  • Genome
  • Immunity, Innate
  • Immunologic Factors
  • Male
  • Nervous System Physiological Phenomena
  • Proteins
  • Sequence Analysis, DNA
  • Signal Transduction
  • Strongylocentrotus purpuratus
  • Transcription Factors