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Identification and characterization of Smyd2: a split SET/MYND domain-containing histone H3 lysine 36-specific methyltransferase that interacts with the Sin3 histone deacetylase complex.

Molecular cancer | 2006

Disrupting the balance of histone lysine methylation alters the expression of genes involved in tumorigenesis including proto-oncogenes and cell cycle regulators. Methylation of lysine residues is commonly catalyzed by a family of proteins that contain the SET domain. Here, we report the identification and characterization of the SET domain-containing protein, Smyd2.

Pubmed ID: 16805913 RIS Download

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Associated grants

  • Agency: NIAID NIH HHS, United States
    Id: R01 AI047209
  • Agency: NHLBI NIH HHS, United States
    Id: R01 HL071160
  • Agency: NIAID NIH HHS, United States
    Id: AI47209
  • Agency: NHLBI NIH HHS, United States
    Id: HL071160

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HEK293T (tool)

RRID:CVCL_0063

Cell line HEK293T is a Transformed cell line with a species of origin Homo sapiens (Human)

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NIH 3T3 (tool)

RRID:CVCL_0594

Cell line NIH 3T3 is a Spontaneously immortalized cell line with a species of origin Mus musculus

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