When the brain loses its self: prefrontal inactivation during sensorimotor processing.
A common theme in theories of subjective awareness poses a self-related "observer" function, or a homunculus, as a critical element without which awareness can not emerge. Here, we examined this question using fMRI. In our study, we compared brain activity patterns produced by a demanding sensory categorization paradigm to those engaged during self-reflective introspection, using similar sensory stimuli. Our results show a complete segregation between the two patterns of activity. Furthermore, regions that showed enhanced activity during introspection underwent a robust inhibition during the demanding perceptual task. The results support the notion that self-related processes are not necessarily engaged during sensory perception and can be actually suppressed.
Pubmed ID: 16630842 RIS Download
Acoustic Stimulation | Adult | Brain Mapping | Female | Humans | Magnetic Resonance Imaging | Male | Photic Stimulation | Prefrontal Cortex | Self Concept