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Gene expression profiles in developing nephrons using Lim1 metanephric mesenchyme-specific conditional mutant mice.

BMC nephrology | 2006

Lim1 is a homeobox gene that is essential for nephrogenesis. During metanephric kidney development, Lim1 is expressed in the nephric duct, ureteric buds, and the induced metanephric mesenchyme. Conditional ablation of Lim1 in the metanephric mesenchyme blocks the formation of nephrons at the nephric vesicle stage, leading to the production of small, non-functional kidneys that lack nephrons.

Pubmed ID: 16464245 RIS Download

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Associated grants

  • Agency: NEI NIH HHS, United States
    Id: EY012311
  • Agency: NICHD NIH HHS, United States
    Id: HD30284
  • Agency: NCI NIH HHS, United States
    Id: P30 CA016672
  • Agency: NCI NIH HHS, United States
    Id: CA16672
  • Agency: NICHD NIH HHS, United States
    Id: R37 HD030284
  • Agency: NEI NIH HHS, United States
    Id: R01 EY012311
  • Agency: NICHD NIH HHS, United States
    Id: R01 HD030284

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UniGene (tool)

RRID:SCR_004405

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on January 11, 2023. Web tool for an organized view of the transcriptome. Collection of the computationally identified transcripts from the same locus. Information on protein similarities, gene expression, cDNA clones, and genomic location. System for automatically partitioning GenBank sequences into a non redundant set of gene oriented clusters.

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