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A genome-wide map of conserved microRNA targets in C. elegans.

Current biology : CB | 2006

Metazoan miRNAs regulate protein-coding genes by binding the 3' UTR of cognate mRNAs. Identifying targets for the 115 known C. elegans miRNAs is essential for understanding their function.

Pubmed ID: 16458514 RIS Download

Research resources used in this publication

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Associated grants

  • Agency: NICHD NIH HHS, United States
    Id: R01-HD046236
  • Agency: NHGRI NIH HHS, United States
    Id: R01-HG02362
  • Agency: NICHD NIH HHS, United States
    Id: R21-HD049435

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This is a list of tools and resources that we have found mentioned in this publication.


WormBase (tool)

RRID:SCR_003098

Central data repository for nematode biology including complete genomic sequence, gene predictions and orthology assignments from range of related nematodes.Data concerning genetics, genomics and biology of C. elegans and related nematodes. Derived from initial ACeDB database of C. elegans genetic and sequence information, WormBase includes genomic, anatomical and functional information of C. elegans, other Caenorhabditis species and other nematodes. Maintains public FTP site where researchers can find many commonly requested files and datasets, WormBase software and prepackaged databases.

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RNAiDB (tool)

RRID:SCR_007900

It provides access to results from RNAi interference studies in C. elegans, including images, movies, phenotypes, and graphical maps. RNAiDB contains all published RNAi experiments in C. elegans that have been deposited in WormBase, including data from the literature and published large-scale RNAi studies. RNAi to gene mappings for all experiments have been re-analyzed using ePCR and/or a sliding n-mer window method to identify all genes in different genomic locations that may potentially be inhibited by each experiment. Gene maps showing canonical and putative alternate mappings are displayed graphically on RNAi Experiment and Gene/ORF card pages.

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