BioModels Database (http://www.ebi.ac.uk/biomodels/), part of the international initiative BioModels.net, provides access to published, peer-reviewed, quantitative models of biochemical and cellular systems. Each model is carefully curated to verify that it corresponds to the reference publication and gives the proper numerical results. Curators also annotate the components of the models with terms from controlled vocabularies and links to other relevant data resources. This allows the users to search accurately for the models they need. The models can currently be retrieved in the SBML format, and import/export facilities are being developed to extend the spectrum of formats supported by the resource.
Pubmed ID: 16381960 RIS Download
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View all literature mentionsFor computational modeling to become more widely used in biological research, researchers must be able to exchange and share their results. The development and broad acceptance of common model representation formats such as SBML is a crucial step in that direction, allowing researchers to exchange and build upon each other''s work with greater ease and accuracy. The BioModels.net project is another step: an international effort to: 1. define agreed-upon standards for model curation 2. define agreed-upon vocabularies for annotating models with connections to biological data resources 3. provide a free, centralized, publicly-accessible database of annotated, computational models in SBML and other structured formats To facilitate assembling useful collections of quantitative models of biological phenomena, it is crucial to establish standards for the vocabularies used in model annotations as well as criteria for minimum quality levels of those models. The BioModels.net project aims to bring together a community of interested researchers to address these issues. We are working towards defining these standards through white papers and process definitions. All of the products of our efforts are open and freely available through this site.
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