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WormBase: better software, richer content.

WormBase (, the public database for genomics and biology of Caenorhabditis elegans, has been restructured for stronger performance and expanded for richer biological content. Performance was improved by accelerating the loading of central data pages such as the omnibus Gene page, by rationalizing internal data structures and software for greater portability, and by making the Genome Browser highly customizable in how it views and exports genomic subsequences. Arbitrarily complex, user-specified queries are now possible through Textpresso (for all available literature) and through WormMart (for most genomic data). Biological content was enriched by reconciling all available cDNA and expressed sequence tag data with gene predictions, clarifying single nucleotide polymorphism and RNAi sites, and summarizing known functions for most genes studied in this organism.

Pubmed ID: 16381915


  • Schwarz EM
  • Antoshechkin I
  • Bastiani C
  • Bieri T
  • Blasiar D
  • Canaran P
  • Chan J
  • Chen N
  • Chen WJ
  • Davis P
  • Fiedler TJ
  • Girard L
  • Harris TW
  • Kenny EE
  • Kishore R
  • Lawson D
  • Lee R
  • Müller HM
  • Nakamura C
  • Ozersky P
  • Petcherski A
  • Rogers A
  • Spooner W
  • Tuli MA
  • Van Auken K
  • Wang D
  • Durbin R
  • Spieth J
  • Stein LD
  • Sternberg PW


Nucleic acids research

Publication Data

January 1, 2006

Associated Grants

  • Agency: Medical Research Council, Id: G0701197
  • Agency: NHGRI NIH HHS, Id: P41-HG02223

Mesh Terms

  • Animals
  • Caenorhabditis elegans
  • Caenorhabditis elegans Proteins
  • DNA, Complementary
  • Databases, Genetic
  • Expressed Sequence Tags
  • Genome, Helminth
  • Genomics
  • Internet
  • Polymorphism, Single Nucleotide
  • RNA Interference
  • Software
  • User-Computer Interface