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SHEsis, a powerful software platform for analyses of linkage disequilibrium, haplotype construction, and genetic association at polymorphism loci.

In multiloci-based genetic association studies of complex diseases, a powerful and high efficient tool for analyses of linkage disequilibrium (LD) between markers, haplotype distributions and many chi-square/p values with a large number of samples has been sought for long. In order to achieve the goal of obtaining meaningful results directly from raw data, we developed a robust and user-friendly software platform with a series of tools for analysis in association study with high efficiency. The platform has been well evaluated by several sets of real data.

Pubmed ID: 15740637


  • Shi YY
  • He L


Cell research

Publication Data

February 2, 2005

Associated Grants


Mesh Terms

  • Genetic Predisposition to Disease
  • Haplotypes
  • Humans
  • Internet
  • Linkage Disequilibrium
  • Polymorphism, Genetic
  • Software