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SHEsis, a powerful software platform for analyses of linkage disequilibrium, haplotype construction, and genetic association at polymorphism loci.

Cell research | Feb 2, 2005

http://www.ncbi.nlm.nih.gov/pubmed/15740637

In multiloci-based genetic association studies of complex diseases, a powerful and high efficient tool for analyses of linkage disequilibrium (LD) between markers, haplotype distributions and many chi-square/p values with a large number of samples has been sought for long. In order to achieve the goal of obtaining meaningful results directly from raw data, we developed a robust and user-friendly software platform with a series of tools for analysis in association study with high efficiency. The platform has been well evaluated by several sets of real data.

Pubmed ID: 15740637 RIS Download

Mesh terms: Genetic Predisposition to Disease | Haplotypes | Humans | Internet | Linkage Disequilibrium | Polymorphism, Genetic | Software