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A dynamic molecular link between the telomere length regulator TRF1 and the chromosome end protector TRF2.

Current biology : CB | 2004

Human telomeres are coated by the telomere repeat binding proteins TRF1 and TRF2, which are believed to function independently to regulate telomere length and protect chromosome ends, respectively.

Pubmed ID: 15380063 RIS Download

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Associated grants

  • Agency: NCI NIH HHS, United States
    Id: R01 CA095099
  • Agency: NCI NIH HHS, United States
    Id: CA09161
  • Agency: NIGMS NIH HHS, United States
    Id: GM07238
  • Agency: NCI NIH HHS, United States
    Id: R01 CA95099

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Fox Chase Cancer Center (tool)

RRID:SCR_004974

Fox Chase Cancer Center is the region''s only hospital devoted entirely to cancer treatment, research and prevention. Our 100-bed hospital, located in Philadelphia, is consistently ranked by U.S. News and World Report among the top cancer centers in the nation. Our nationally and internationally recognized staff provides consultations and treatment recommendations for all types of adult cancer. Fox Chase Cancer Center is an independent, nonprofit institution formed in 1974 by the union of American Oncologic Hospital (one the the nation''s first cancer hospitals, established in 1904) and the Institute for Cancer Research (founded in 1927). Fox Chase was also among the first institutions to be designated a National Cancer Institute Comprehensive Cancer Center in 1974. In September 2000, the Hospital of Fox Chase Cancer Center became the nation''s first comprehensive cancer center and Pennsylvania''s first hospital to receive Magnet status for nursing excellence from the American Nurses Credentialing Center, which renewed this honor in 2004 and again in 2009, making it the first hospital in Pennsylvania to have achieved two successful Magnet renewals. The Women''s Cancer Center builds on Fox Chase''s world-renowned expertise in breast and gynecologic cancers. The Center offers women a place where they can receive coordinated, state-of-the-art care, support services, and education all under one roof.

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