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High frequency of mutations of the PIK3CA gene in human cancers.


Pubmed ID: 15016963


  • Samuels Y
  • Wang Z
  • Bardelli A
  • Silliman N
  • Ptak J
  • Szabo S
  • Yan H
  • Gazdar A
  • Powell SM
  • Riggins GJ
  • Willson JK
  • Markowitz S
  • Kinzler KW
  • Vogelstein B
  • Velculescu VE


Science (New York, N.Y.)

Publication Data

April 23, 2004

Associated Grants

  • Agency: NCI NIH HHS, Id: CA 43460
  • Agency: NCI NIH HHS, Id: CA 57345
  • Agency: NCI NIH HHS, Id: CA 62924
  • Agency: NCI NIH HHS, Id: CA 67900
  • Agency: NCI NIH HHS, Id: CA 88128

Mesh Terms

  • Breast Neoplasms
  • Catalytic Domain
  • Colorectal Neoplasms
  • Glioblastoma
  • Humans
  • Lung Neoplasms
  • Mutation
  • Neoplasms
  • Phosphatidylinositol 3-Kinases
  • Sequence Analysis, DNA
  • Stomach Neoplasms