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FatiGO: a web tool for finding significant associations of Gene Ontology terms with groups of genes.

We present a simple but powerful procedure to extract Gene Ontology (GO) terms that are significantly over- or under-represented in sets of genes within the context of a genome-scale experiment (DNA microarray, proteomics, etc.). Said procedure has been implemented as a web application, FatiGO, allowing for easy and interactive querying. FatiGO, which takes the multiple-testing nature of statistical contrast into account, currently includes GO associations for diverse organisms (human, mouse, fly, worm and yeast) and the TrEMBL/Swissprot GOAnnotations@EBI correspondences from the European Bioinformatics Institute.

Pubmed ID: 14990455


  • Al-Shahrour F
  • Díaz-Uriarte R
  • Dopazo J


Bioinformatics (Oxford, England)

Publication Data

March 1, 2004

Associated Grants


Mesh Terms

  • Algorithms
  • Artificial Intelligence
  • Databases, Genetic
  • Gene Expression Profiling
  • Hypermedia
  • Information Storage and Retrieval
  • Internet
  • Phylogeny
  • Sequence Alignment
  • Sequence Analysis, DNA
  • Software