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WormBase: a multi-species resource for nematode biology and genomics.

WormBase (http://www.wormbase.org/) is the central data repository for information about Caenorhabditis elegans and related nematodes. As a model organism database, WormBase extends beyond the genomic sequence, integrating experimental results with extensively annotated views of the genome. The WormBase Consortium continues to expand the biological scope and utility of WormBase with the inclusion of large-scale genomic analyses, through active data and literature curation, through new analysis and visualization tools, and through refinement of the user interface. Over the past year, the nearly complete genomic sequence and comparative analyses of the closely related species Caenorhabditis briggsae have been integrated into WormBase, including gene predictions, ortholog assignments and a new synteny viewer to display the relationships between the two species. Extensive site-wide refinement of the user interface now provides quick access to the most frequently accessed resources and a consistent browsing experience across the site. Unified single-page views now provide complete summaries of commonly accessed entries like genes. These advances continue to increase the utility of WormBase for C.elegans researchers, as well as for those researchers exploring problems in functional and comparative genomics in the context of a powerful genetic system.

Pubmed ID: 14681445

Authors

  • Harris TW
  • Chen N
  • Cunningham F
  • Tello-Ruiz M
  • Antoshechkin I
  • Bastiani C
  • Bieri T
  • Blasiar D
  • Bradnam K
  • Chan J
  • Chen CK
  • Chen WJ
  • Davis P
  • Kenny E
  • Kishore R
  • Lawson D
  • Lee R
  • Muller HM
  • Nakamura C
  • Ozersky P
  • Petcherski A
  • Rogers A
  • Sabo A
  • Schwarz EM
  • Van Auken K
  • Wang Q
  • Durbin R
  • Spieth J
  • Sternberg PW
  • Stein LD

Journal

Nucleic acids research

Publication Data

January 1, 2004

Associated Grants

  • Agency: NHGRI NIH HHS, Id: P41-HG02223

Mesh Terms

  • Animals
  • Caenorhabditis
  • Caenorhabditis elegans
  • Computational Biology
  • Databases, Genetic
  • Genomics
  • Information Storage and Retrieval
  • Internet
  • User-Computer Interface