We have updated our privacy policy. If you have any question, contact us at privacy@scicrunch.org. Dismiss and don't show again

Searching across hundreds of databases

Our searching services are busy right now. Your search will reload in five seconds.

Forgot Password

If you have forgotten your password you can enter your email here and get a temporary password sent to your email.

Dissociable executive functions in the dynamic control of behavior: inhibition, error detection, and correction.

NeuroImage | Dec 24, 2002

The present study employed event-related fMRI and EEG to investigate the biological basis of the cognitive control of behavior. Using a GO/NOGO task optimized to produce response inhibitions, frequent commission errors, and the opportunity for subsequent behavioral correction, we identified distinct cortical areas associated with each of these specific executive processes. Two cortical systems, one involving right prefrontal and parietal areas and the second regions of the cingulate, underlay inhibitory control. The involvement of these two systems was predicated upon the difficulty or urgency of the inhibition and each was employed to different extents by high- and low-absent-minded subjects. Errors were associated with medial activation incorporating the anterior cingulate and pre-SMA while behavioral alteration subsequent to errors was associated with both the anterior cingulate and the left prefrontal cortex. Furthermore, the EEG data demonstrated that successful response inhibition depended upon the timely activation of cortical areas as predicted by race models of response selection. The results highlight how higher cognitive functions responsible for behavioral control can result from the dynamic interplay of distinct cortical systems.

Pubmed ID: 12498755 RIS Download

Mesh terms: Adult | Attention | Brain Mapping | Cerebral Cortex | Dominance, Cerebral | Echo-Planar Imaging | Electroencephalography | Female | Frontal Lobe | Gyrus Cinguli | Humans | Image Processing, Computer-Assisted | Imaging, Three-Dimensional | Male | Middle Aged | Nerve Net | Neural Inhibition | Pattern Recognition, Visual | Psychomotor Performance | Putamen | Reaction Time | Serial Learning | Thalamus

Research resources used in this publication

None found

Research tools detected in this publication

None found

Data used in this publication

None found

Associated grants

  • Agency: NIDA NIH HHS, Id: DA09465
  • Agency: NIDA NIH HHS, Id: DA14100-01
  • Agency: NCRR NIH HHS, Id: M01 RR00058

SumsDB (Data, Activation Foci)

Publication data is provided by the National Library of Medicine ® and PubMed ®. Data is retrieved from PubMed ® on a weekly schedule. For terms and conditions see the National Library of Medicine Terms and Conditions.

We have not found any resources mentioned in this publication.