Literature search services are currently unavailable. During our hosting provider's UPS upgrade we experienced a hardware failure and are currently working to resolve the issue.

Preparing your results

Our searching services are busy right now. Your search will reload in five seconds.

Forgot Password

If you have forgotten your password you can enter your email here and get a temporary password sent to your email.

Neural responses during anticipation of a primary taste reward.

The aim of this study was to determine the brain regions involved in anticipation of a primary taste reward and to compare these regions to those responding to the receipt of a taste reward. Using fMRI, we scanned human subjects who were presented with visual cues that signaled subsequent reinforcement with a pleasant sweet taste (1 M glucose), a moderately unpleasant salt taste (0.2 M saline), or a neutral taste. Expectation of a pleasant taste produced activation in dopaminergic midbrain, posterior dorsal amygdala, striatum, and orbitofrontal cortex (OFC). Apart from OFC, these regions were not activated by reward receipt. The findings indicate that when rewards are predictable, brain regions recruited during expectation are, in part, dissociable from areas responding to reward receipt.

Pubmed ID: 11879657


  • O'Doherty JP
  • Deichmann R
  • Critchley HD
  • Dolan RJ



Publication Data

February 28, 2002

Associated Grants


Mesh Terms

  • Adolescent
  • Adult
  • Animals
  • Brain
  • Brain Mapping
  • Cues
  • Emotions
  • Female
  • Glucose
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Reinforcement (Psychology)
  • Reward
  • Salts
  • Taste