Gene Expression Omnibus: NCBI gene expression and hybridization array data repository.
The Gene Expression Omnibus (GEO) project was initiated in response to the growing demand for a public repository for high-throughput gene expression data. GEO provides a flexible and open design that facilitates submission, storage and retrieval of heterogeneous data sets from high-throughput gene expression and genomic hybridization experiments. GEO is not intended to replace in house gene expression databases that benefit from coherent data sets, and which are constructed to facilitate a particular analytic method, but rather complement these by acting as a tertiary, central data distribution hub. The three central data entities of GEO are platforms, samples and series, and were designed with gene expression and genomic hybridization experiments in mind. A platform is, essentially, a list of probes that define what set of molecules may be detected. A sample describes the set of molecules that are being probed and references a single platform used to generate its molecular abundance data. A series organizes samples into the meaningful data sets which make up an experiment. The GEO repository is publicly accessible through the World Wide Web at http://www.ncbi.nlm.nih.gov/geo.
Pubmed ID: 11752295
- Edgar R
- Domrachev M
- Lash AE
Nucleic acids research
January 1, 2002
- Database Management Systems
- Databases, Genetic
- Gene Expression Profiling
- Information Storage and Retrieval
- National Library of Medicine (U.S.)
- Oligonucleotide Array Sequence Analysis
- United States