Structural requirements for the beta1 integrin functions in cell adhesion, spreading and signaling have been well documented mainly for fibroblasts. In this study, we examined the reason for the reduced surface expression of beta1 integrin in human breast cancer MCF-7 cells compared to normal human breast epithelial (HBE) cells, both of which adhered to collagen type IV.
Pubmed ID: 11716783 RIS Download
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Cell line MCF-7 is a Cancer cell line with a species of origin Homo sapiens (Human)
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