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Targeted inactivation of the sodium-calcium exchanger (Ncx1) results in the lack of a heartbeat and abnormal myofibrillar organization.

Pubmed ID: 11344090


  • Koushik SV
  • Wang J
  • Rogers R
  • Moskophidis D
  • Lambert NA
  • Creazzo TL
  • Conway SJ


FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Publication Data

May 9, 2001

Associated Grants


Mesh Terms

  • Animals
  • Calcium
  • Embryonic and Fetal Development
  • Gene Targeting
  • Genes, Reporter
  • Heart
  • Immunohistochemistry
  • Mice
  • Mice, Transgenic
  • Morphogenesis
  • Myocardial Contraction
  • Myocardium
  • Sodium-Calcium Exchanger