Forgot Password

If you have forgotten your password you can enter your email here and get a temporary password sent to your email.

Automated Talairach atlas labels for functional brain mapping.

An automated coordinate-based system to retrieve brain labels from the 1988 Talairach Atlas, called the Talairach Daemon (TD), was previously introduced [Lancaster et al., 1997]. In the present study, the TD system and its 3-D database of labels for the 1988 Talairach atlas were tested for labeling of functional activation foci. TD system labels were compared with author-designated labels of activation coordinates from over 250 published functional brain-mapping studies and with manual atlas-derived labels from an expert group using a subset of these activation coordinates. Automated labeling by the TD system compared well with authors' labels, with a 70% or greater label match averaged over all locations. Author-label matching improved to greater than 90% within a search range of +/-5 mm for most sites. An adaptive grey matter (GM) range-search utility was evaluated using individual activations from the M1 mouth region (30 subjects, 52 sites). It provided an 87% label match to Brodmann area labels (BA 4 & BA 6) within a search range of +/-5 mm. Using the adaptive GM range search, the TD system's overall match with authors' labels (90%) was better than that of the expert group (80%). When used in concert with authors' deeper knowledge of an experiment, the TD system provides consistent and comprehensive labels for brain activation foci. Additional suggested applications of the TD system include interactive labeling, anatomical grouping of activation foci, lesion-deficit analysis, and neuroanatomy education.

Pubmed ID: 10912591


  • Lancaster JL
  • Woldorff MG
  • Parsons LM
  • Liotti M
  • Freitas CS
  • Rainey L
  • Kochunov PV
  • Nickerson D
  • Mikiten SA
  • Fox PT


Human brain mapping

Publication Data

July 9, 2000

Associated Grants

  • Agency: NLM NIH HHS, Id: 1 RO1 LM06858-01
  • Agency: NIMH NIH HHS, Id: 5 P01 MH52176-07

Mesh Terms

  • Anatomy, Artistic
  • Brain
  • Brain Mapping
  • Cerebral Cortex
  • Humans
  • Image Processing, Computer-Assisted
  • Magnetic Resonance Imaging
  • Medical Illustration
  • Task Performance and Analysis
  • Tomography, Emission-Computed
  • Tomography, Emission-Computed, Single-Photon