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High-efficiency deleter mice show that FLPe is an alternative to Cre-loxP.

Pubmed ID: 10835623


  • Rodríguez CI
  • Buchholz F
  • Galloway J
  • Sequerra R
  • Kasper J
  • Ayala R
  • Stewart AF
  • Dymecki SM


Nature genetics

Publication Data

June 29, 2000

Associated Grants

  • Agency: NHGRI NIH HHS, Id: F31 HG000180

Mesh Terms

  • Amino Acid Substitution
  • Animals
  • DNA Nucleotidyltransferases
  • Enzyme Stability
  • Female
  • Genes, Reporter
  • Genetic Engineering
  • Integrases
  • Male
  • Mice
  • Mice, Transgenic
  • Mutagenesis, Site-Directed
  • Organ Specificity
  • Recombination, Genetic
  • Sequence Deletion
  • Transgenes
  • Viral Proteins