Preparing your results

Our searching services are busy right now. Your search will reload in five seconds.

Forgot Password

If you have forgotten your password you can enter your email here and get a temporary password sent to your email.

A multimodal cortical network for the detection of changes in the sensory environment.

Sensory stimuli undergoing sudden changes draw attention and preferentially enter our awareness. We used event-related functional magnetic-resonance imaging (fMRI) to identify brain regions responsive to changes in visual, auditory and tactile stimuli. Unimodally responsive areas included visual, auditory and somatosensory association cortex. Multimodally responsive areas comprised a right-lateralized network including the temporoparietal junction, inferior frontal gyrus, insula and left cingulate and supplementary motor areas. These results reveal a distributed, multimodal network for involuntary attention to events in the sensory environment. This network contains areas thought to underlie the P300 event-related potential and closely corresponds to the set of cortical regions damaged in patients with hemineglect syndromes.

Pubmed ID: 10700261


  • Downar J
  • Crawley AP
  • Mikulis DJ
  • Davis KD


Nature neuroscience

Publication Data

March 11, 2000

Associated Grants


Mesh Terms

  • Adolescent
  • Adult
  • Attention
  • Auditory Perception
  • Brain Mapping
  • Cerebral Cortex
  • Dominance, Cerebral
  • Event-Related Potentials, P300
  • Evoked Potentials, Somatosensory
  • Female
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Perceptual Disorders
  • Physical Stimulation
  • Touch
  • Visual Perception