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ALFRED: an allele frequency database for diverse populations and DNA polymorphisms.

Nucleic acids research | Jan 1, 2000

http://www.ncbi.nlm.nih.gov/pubmed/10592274

We have developed a publicly accessible database (ALFRED, the ALlele FREquency Database) that catalogues allele frequency data for a wide range of population samples and DNA polymorphisms. This database is web-accessible through our laboratory (Kidd Lab) Web site: http://info.med.yale.edu/genetics/kkidd. ALFRED currently contains data on 60 populations and 156 genetic systems including single nucleotide polymorphisms (SNPs), short tandem repeat polymorphisms (STRPs), variable number of tandem repeats (VNTRs) and insertion-deletion polymorphisms. While data are not available for all population-DNA polymorphism combinations, over 2000 allele frequency tables have been entered. Our database is designed (i) to address our specific research requirements as well as broader scientific objectives; (ii) to allow researchers and interested educators to easily navigate and retrieve data of interest to them; and (iii) to integrate links to other related public databases such as dbSNP, GenBank and PubMed.

Pubmed ID: 10592274 RIS Download

Mesh terms: Alleles | Databases, Factual | Gene Frequency | Genetic Variation | Humans | Polymorphism, Genetic | User-Computer Interface