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ALFRED: an allele frequency database for diverse populations and DNA polymorphisms.

We have developed a publicly accessible database (ALFRED, the ALlele FREquency Database) that catalogues allele frequency data for a wide range of population samples and DNA polymorphisms. This database is web-accessible through our laboratory (Kidd Lab) Web site: http://info.med.yale.edu/genetics/kkidd. ALFRED currently contains data on 60 populations and 156 genetic systems including single nucleotide polymorphisms (SNPs), short tandem repeat polymorphisms (STRPs), variable number of tandem repeats (VNTRs) and insertion-deletion polymorphisms. While data are not available for all population-DNA polymorphism combinations, over 2000 allele frequency tables have been entered. Our database is designed (i) to address our specific research requirements as well as broader scientific objectives; (ii) to allow researchers and interested educators to easily navigate and retrieve data of interest to them; and (iii) to integrate links to other related public databases such as dbSNP, GenBank and PubMed.

Pubmed ID: 10592274

Authors

  • Cheung KH
  • Osier MV
  • Kidd JR
  • Pakstis AJ
  • Miller PL
  • Kidd KK

Journal

Nucleic acids research

Publication Data

January 1, 2000

Associated Grants

  • Agency: NIAAA NIH HHS, Id: AA09379
  • Agency: NLM NIH HHS, Id: LM05583
  • Agency: NLM NIH HHS, Id: T15 LM07056

Mesh Terms

  • Alleles
  • Databases, Factual
  • Gene Frequency
  • Genetic Variation
  • Humans
  • Polymorphism, Genetic
  • User-Computer Interface