SciCrunch Registry/resources/Tools/searchResource NameARTProper CitationART (RRID:SCR_006538)AbbreviationsARTResource Typesoftware resourceDescriptionA set of simulation tools to generate synthetic next-generation sequencing reads. ART simulates sequencing reads by mimicking real sequencing process with empirical error models or quality profiles summarized from large recalibrated sequencing data. ART can also simulate reads using user own read error model or quality profiles. ART supports simulation of single-end, paired-end/mate-pair reads of three major commercial next-generation sequencing platforms: Illumina''''s Solexa, Roche''''s 454 and Applied Biosystems'''' SOLiD. ART can be used to test or benchmark a variety of method or tools for next-generation sequencing data analysis, including read alignment, de novo assembly, SNP and structure variation discovery. ART is implemented in C++ with optimized algorithms and is highly efficient in read simulation. ART outputs reads in the FASTQ format, and alignments in the ALN format. ART can also generate alignments in the SAM alignment or UCSC BED file format.Keywordsnext-generation sequencingResource Relationshipsis listed by::OMICtools::SCR_002250; is listed by::Debian::SCR_006638; is listed by::SoftCite::SCR_024411; is related to::1000 Genomes: A Deep Catalog of Human Genetic Variation::SCR_006828; has parent organization::National Institute of Environmental Health Sciences::SCR_011430Related ConditionFundingDefining CitationPMID:22199392, DOI:10.1093/bioinformatics/btr708AvailabilityFree, PublicSpecification URLAlternate IDsOMICS_00247Alternate URLshttps://sources.debian.org/src/augustus/Old URLsParent OrganizationResource IDSCR_006538SynonymsART - Set of Simulation ToolsLicenseLicense URLsRecord Last Update20260919T195113+0000Record Creation Time20220129T080236+0000Mentions Count9v_uuid77ee4ac3-b99f-5c3c-bdfc-745831b5a773Publications that use this research resourcePMID:39347649PMID:36939008PMID:36824522PMID:36304115PMID:36824342PMID:29762668PMID:25711446PMID:26460497PMID:23335788