URL: http://great.stanford.edu/public/html/splash.php
Proper Citation: GREAT: Genomic Regions Enrichment of Annotations Tool (RRID:SCR_005807)
Description: Data analysis service that predicts functions of cis-regulatory regions identified by localized measurements of DNA binding events across an entire genome. Whereas previous methods took into account only binding proximal to genes, GREAT is able to properly incorporate distal binding sites and control for false positives using a binomial test over the input genomic regions. GREAT incorporates annotations from 20 ontologies and is available as a web application. The utility of GREAT extends to data generated for transcription-associated factors, open chromatin, localized epigenomic markers and similar functional data sets, and comparative genomics sets. Platform: Online tool
Abbreviations: GREAT
Synonyms: Genomic Regions Enrichment of Annotations Tool (GREAT), Genomic Regions Enrichment of Annotations Tool
Resource Type: analysis service resource, software resource, source code, production service resource, service resource, data analysis service
Defining Citation: PMID:20436461, PMID:23814184
Keywords: term enrichment, cis-regulatory region, function, gene, genomic, annotation, ontology, chromatin immunoprecipitation, sequencing, chip-seq, comparative genomics, transcription factor binding
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