URL: https://web.expasy.org/cellosaurus/CVCL_0125
Proper Citation: (BCRJ Cat# 0022, RRID:CVCL_0125)
Description: Cell line 4T1 is a Cancer cell line with a species of origin Mus musculus (Mouse)
Sex: Female
Disease: Malignant neoplasms of the mouse mammary gland
Defining Citation: PMID:10411109, PMID:26857856, PMID:27177471, PMID:31220119
Comments: Breed/subspecies: BALB/cfC3H., Derived from sampling site: Mammary gland., Omics: Transcriptome analysis by microarray., Doubling time: 12.6 hours (ATCC=CRL-2539)., Characteristics: Widely used model in cancer research due to its high similarity to human breast cancer. The tumor growth and metastatic spread of 4T1 cells closely mimic the behavior of human breast cancer. The 4T1 cell line is considered an animal model for stage IV human breast cancer, as it is able to spontaneously metastasize in both post-operative and non-surgical models (CLS)., Characteristics: Metastatic.
Category: Cancer cell line
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Source: Cellosaurus
